I have 2 appliances, 1 1000 Watts and the other 1200 watts. Can I run both off a 20 AMP circuit using 12 or 14 gauge wire with the first connection on a GFI.

Maybe. What are the appliances? Is the voltage 120 V?

I = (1000+1200)/120 = 18.33 A

12 AWG would be fused at 20 Amps.

But, need to know what the appliances are, especially if they are space heating.

Maybe. What are the appliances? Is the voltage 120 V?

I = (1000+1200)/120 = 18.33 A

12 AWG would be fused at 20 Amps.

But, need to know what the appliances are, especially if they are space heating.

2 Microwaves (one is a Convection/Microwave)

Then technicly, it will work.