Hey I have recently purchases a pair of glasses and I seem to have a situation with the tightening of a screw from my nose clips or buds. I'm trying to tighten my nose buds with the screw however it seems as though it is going 360 non stop it is like as though it isn't tightening, why is this I have plastic glasses and the screws are the right match

You've managed to strip the threads. Hopefully, only the screw's threads are damaged. Stop in at an optical shop and ask them for another screw. They may have to re-thread the hole and give you a larger screw.

Agreed. If this is a new pair see if they will replace them under a warranty. There is a reason that Opticians have jobs. Messing with screws yourself could be bad. Most opticians have self-tapping screws which will create a new thread with a new screw.