I have this prob. Many times specially when I play sounds or some graphics I had the prob that the mouse and the keyboard locked and I can do nothing to the PC except reseting it. Anyone knows a solution

I have a HP OmniBook XE3 with windows XP 1.06 GHz

Have you done standard maintenance (Disk Checkup, Defrag, Virus and spoyware scans)?

Yes I've done the standard maintenance . Even I removed and reinstalled the real player because this prob happened a lot when using real player. But still