Does ibuprofen have bad side effects if taken on a daily basis? I have been taking it for about a month on a daily basis, and I've been experiencing some nausea and upset stomach from time to time. A friend told me experiencing irritates the stomach lining, is there any truth to this information?

I did a bit of research on the subject because I used to take it daily for migraines...

So, this is the first thing to read:
DRUG INTERACTIONS: Ibuprofen is associated with several suspected or probable interactions that can affect the action of other drugs. Ibuprofen may increase the blood levels of lithium (http://www.medicinenet.com/script/main/art.asp?articlekey=6178) (Eskalith) by reducing the excretion of lithium by the kidneys. Increased levels of lithium may lead to lithium toxicity. Ibuprofen may reduce the blood pressure-lowering effects of drugs that are given to reduce blood pressure. This may occur because prostaglandins play a role in the regulation of blood pressure. When ibuprofen is used in combination with aminoglycosides [for example, gentamicin (http://www.medicinenet.com/script/main/art.asp?articlekey=45172) (Garamycin)] the blood levels of the aminoglycoside may increase, presumably because the elimination of aminoglycosides from the body is reduced. This may lead to aminoglycoside-related side effects. Individuals taking oral blood thinners or anticoagulants [for example, warfarin (http://www.medicinenet.com/script/main/art.asp?articlekey=727) (Coumadin)] should avoid ibuprofen because ibuprofen also thins the blood, and excessive blood thinning may lead to bleeding.

SIDE EFFECTS: The most common side effects from ibuprofen are rash (http://www.medicinenet.com/script/main/art.asp?articlekey=1992), ringing in the ears (http://www.medicinenet.com/script/main/art.asp?articlekey=496), headaches (http://www.medicinenet.com/script/main/art.asp?articlekey=20628), dizziness, drowsiness, abdominal pain (http://www.medicinenet.com/script/main/art.asp?articlekey=1908), nausea (http://www.medicinenet.com/script/main/art.asp?articlekey=41943), diarrhea (http://www.medicinenet.com/script/main/art.asp?articlekey=1900), constipation (http://www.medicinenet.com/script/main/art.asp?articlekey=331) and heartburn (http://www.medicinenet.com/script/main/art.asp?articlekey=375). NSAIDs reduce the ability of blood to clot and therefore increase bleeding after an injury. Ibuprofen may cause ulceration of the stomach or intestine, and the ulcers may bleed. Sometimes, ulceration can occur without abdominal pain, and black, tarry stools, weakness, and dizziness upon standing (orthostatic hypotension) due to bleeding may be the only signs of an ulcer. NSAIDs reduce the flow of blood to the kidneys and impair function of the kidneys. The impairment is most likely to occur in patients who already have impaired function of the kidney or congestive heart failure (http://www.medicinenet.com/script/main/art.asp?articlekey=1930), and use of NSAIDs in these patients should be cautious. People who are allergic to other NSAIDs, including aspirin (http://www.medicinenet.com/script/main/art.asp?articlekey=697), should not use ibuprofen. Individuals with asthma (http://www.medicinenet.com/script/main/art.asp?articlekey=284) are more likely to experience allergic reactions to ibuprofen and other NSAIDs. Fluid retention (edema (http://www.medicinenet.com/script/main/art.asp?articlekey=12699)), blood clots, heart attacks (http://www.medicinenet.com/script/main/art.asp?articlekey=379), hypertension (http://www.medicinenet.com/script/main/art.asp?articlekey=378) and heart failure (http://www.medicinenet.com/script/main/art.asp?articlekey=42321) have also been associated with the use of NSAIDs.



Hope this helps!

I believe this is the article in which Chi found the above information. It is ALWAYS recommended that you site your sources.

ibuprofen (Advil, Motrin) – drug class, medical uses, medication side effects, and drug interactions by MedicineNet.com (http://www.medicinenet.com/ibuprofen/article.htm)

It is, sorry about that...