I have two prescriptions: metoprolol tartarate 25 mg and metoprolol succ er 25 mg. Does anyone know what the effective difference is? :confused: Can one replace the other? Or be used instead of the other? Thanks! :)

They are interchangeable. It's simply that the "ER" is an Extended Release version and seems to be better tolerated and is longer acting.

The extended release [ toprol xl? ] can be taken once a day and is probably more costly.


PLain old generic metoprolol [ less costly ] will act more quickly and not last 24 hours, therefore it is usually dosed twice a day. If you take this once a day it may not give you the blood pressure control [ important if you have angina or heart disease ] that you need.



Please let your doctor know of your dilemma here, and get exact instructions and dosage.

inthebox is right.