I have locked my E drive with Easy drive lock.v4 and now when I enter password it says access denied,now what should I do bcoz I have very important data in that drive

Contact the software vendor.

First, may I call your attention to the guidelines for using the comments feature found here:

https://www.askmehelpdesk.com/feedback/using-comments-feature-24951.html

Your question was about the use of a specific software package. Unless someone here is intimately familiar with that package, they are not going to be able to help you. This is a problem with the way the software works, therefore the people who support that software are the best ones to provide help with it. So not only was my answer not "rubbish" (and, therefore, you rating inappropriate), it was the best and most useful answer you will probably get here.