My brother want to apply spounce visa. His wife is a nationality holder of UK, she is now in UK and he is in Pakisatn, I want what documents he need to apply spounce visa?

You would have to contact your embassy in the uk or the uk embassy they can give you all the information you need. The site is The High Commission for Pakistan in United Kingdom (http://www.phclondon.org/HC/index.asp)