Can anybody tell about loan against mutual fund?

Please clarify your question - what exactly do you want to know? Are you asking about using a mutual fund as collateral for a personal loan? If so, it can be done (if your lender is willing), but you will most likely have to provide a physical certificate of ownership, much like a stock certificate. This site may be of help: https://finance.zacks.com/can-use-mutual-fund-collateral-11131.html