I turned my garage into a workshop and want to install permanent heat and air and am going to buy a ductless a/c & heat pump. Is it better to buy it with 220 volts or with 110 volts?

220 Volts, less amps, less electricity.

220 Volts, less amps, less electricity.
Watts is what are used, not Amperes. Watts= Volts X Amps is the same and therefore the same power is used. 240 is a bit more efficient under load and running plus smaller wire.