I have been taking opana ir 5mg for about a week now for back and knee pain, my blood pressure is high now, it the opana the cause?

Probably not, oxymorphone aka opana usually causes hypotension which means it should lower your blood pressure.

If your blood pressure has suddenly raised you need to speak to your doctor.
If it's over 180/120 you need to go to the ER asap!

Thank You.