Mumma 2and half year old cat, was a stray but been living with us for about 1year and half. Can stroke her. Not pick up. We have moved 3 times in the past year. Now finally in our own spot for good.

Mumma is now pooping and peeing on my bathroom mats as well as clothes if I leave my tracksuit pants on the side of the bath.

I have also noticed she sleeps all day in the spare room bathroom sink.
At night her daughter (Brain +-1 and half years old) wants to play. And Mumma just growels at her...

What do I do?

You don't say how long you have been in this new place?
She sounds either unhappy about the move, something in another part of the house scared her, or she's in pain. Has she been to a vet in the last year? Does she have a litter box, or is she supposed to go outside? Where is the litter box relative to the bathroom? Does she avoid the rest of the house?

We been in the new place for about a month

We been in our new spot for about a month, 2200sqft.
Mumma walks around everywhere in the house.
Went to the vet about a year ago for the spay. She is a stray, we can stroke her but not pick up. We were in a villa which had a big beach in front of the house with a fish market and other stray cats around, it is were she was born.
She has a littler box and uses it all the time, she even uses the spare toilet. (squats over the bowl). The littler box is in the spare bathroom on other side of the house to my bathroom.