Replaced main relay;car starts and runs about 90 mim. Then dies. After 30 min. car restarts runs 90 min.dies why?

Replace the Ignition Control Module (ICM) and coil:

https://www.askmehelpdesk.com/cars-trucks/faq-how-troubleshoot-repair-maintain-hondas-selected-other-vehicles-46563-4.html#post265896