What is the best way to cut a hole in corion countertops. I have a desk in my kitchen with corion countertops and I want to cut a hole in it for computer cords.

You can cut Corian pretty much like a hard wood. Use a hole saw and a electric drill. Select a hole saw that will match a plastic insert for desk top wiring. Your cut will be rough but you can sand smooth with 120 paper, then finer, on a drum, same drill