Sometimes my remote(s) unlocks the doors sometimes it does not. When the remote(s) does not unlock the doors and I unlock the driver's door manually with the key it sets off the panic alarm (horn, lights, instrument panel flashes). This alarm goes on for a full 2 minutes. When the remote(s) work all functions of the remote work. Any suggestions on what might be wrong? Or how to fix it?

Try spraying the buttons on the remote with WD-40.