There was this cartoon I watched when I was little - it was either in the late 80s or early 90s - the characters were animals who were a mix of two different animals (as in, a lion mixed with a hippo, a zebra mixed with a monkey, etc - those aren't specific characters, I don't think - just examples)... does anyone know what I'm talking about? It's driving me freakin' CRAZY!

I'm ALMOST certain I know the name of this for you! It was called The Wuzzles, and yes, all the characters were a mix of two different animals! My favorite was the half lion-half bumblebee named Bumblelion! Hope this puts your mind at ease! :)

Wuzzles

I believe you're thinking of the Adventures of the Little Koala. :)