| I'm not a medical practitioner of any kind... just someone who was on depo for about 4 years.
I had none of the side effects with depo that I had with the pill -- it seemed like it was just a little pinch a few times a year, and poof -- no worries about pregnancy. I was thrilled.
However, I did eventually notice that my libido had decreased, to the point where I had no sex drive at all. At first I didn't correlate this with the depo; I just went to talk with my OB-GYN about it, and she said, "of course you have no sex drive. Did you know that they give depo to pedophiles to reduce their libido? You basically have the hormones of a post-menopausal woman." I was shocked -- out of all the doctors and nurses who had given me the shot over the years, not one of them had mentioned this.
When I thought about it, I realized that the decrease in libido did correlate with the time I started depo. But it was so gradual that I didn't realize it was happening at first.
It took me 6 months to get my period back, but it has taken nearly two years for my sex drive to come back to anything approaching what it was before depo.
Again, I'm not a medical expert, but if I were you I'd stop the depo not just because of conception timing worries, but because I'd hope to avoid potential marital problems arising from having no sexual desire for my husband. | 
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