Startup...?

Can you elaborate a little, what version of windows, what is the folder that keeps opening, what have you already tried (antivirus, antispyware, etc)
Have you checked your startup folder from the start - programs - startup.

There's more but we need more info really.

Also try Start > Run, type in "msconfig" and click on Enter or OK, click the "Startup" tab. Browse through there and uncheck anything that looks like the folder name. Click OK at bottom of that window and it will ask you if you want to reboot; do it if you are not in the middle of anything at the time.

Well I tried that one (msconfig) too but no used... I'm using win xp sp2 and the folder is a imesh folder but I already uninstall this software...

Hi,
Here is a link for some very good information:

http://www.wellesley.edu/Computing/R...P2P/imesh.html

Imesh contains Spyware and Advertising; which will not go away with just uninstalling Imesh, as you already know.
The link above will give you some steps to take, to try ridding your computer of it.
Also, do you have any Spyware/Advertising removal programs? If not, here are some, free, work great, with steps on how to use them:

If you think you already have Spyware/Advertising Ware in your computer, run these as follows:

AdAware at:
http://www.lavasoftusa.com
Download: AdAware_SE V 1.06

CWShredder at:
http://www.trendmicro.com/cwshredder/
Click on the "Remove CoolWeb Search" button to download

Both of the above programs run better and much faster when run in SafeMode.

To get into SafeMode:
Re-boot the computer, and immediately after starting up, Press and hold down, F8, at top of keypad.
When the options show on the screen, use the up and down arrow keys on the keyboard to select
"Safe Mode".
Press Enter

It's best to run the AdAware scan first; 3 times; then re-boot.
Then, run the AdAware scan again 3 times. Then, run CWShredder.
Re- Boot.
Reason for running so many times:
Some of these trojans' files can be deleted the first time; leaving some others; but on re-boot, they re-write the files that were deleted.
Running multiple times deletes most of it the first
Time.

If you wish to have a great program, after you clean out Spyware/Advertising Ware:
This program stops this stuff from getting into the computer in the first place, by placing URL's in the browser, stopping them instantly. One of the Very Best free programs anyone can download!

SpyWare Blaster 3.4

http://www.javacoolsoftware.com/sbdownload.html

Free online scan at:
http://www.trendmicro.com/spyware-scan/

Before I download any new programs, I usually go to http://www.cnet/downloads , and search for the program name. There will be reviews, usually stating if the program contains spyware. In that way, one will know if the program you are interested in might contain spyware.
I do wish you good luck, and it the above doesn't fix it, please post back.

Thanks for your advice guys but I'd just delete the folder and that would fixed my problem...