About an hour after my wife goes to bed, the back of her calves begin to itch and becomes a red rash with red bumps (at the hair follicles?) . It makes her loose sleep as she gets up usually twice to apply cortisone cream. She showers before bed and we've tried different body soaps. She's tried showering in the morning. We've tried different laundry soaps for the bedding. All to no avail. It seems odd that it would only occur at night, and has no effect on me (we sleep together}. The Dr. says it's irritated hair follicles, but not why or what to do for it. Any suggestions/medications?

Thank you,
Mike

jonalisa

Has she tried Benadryl?