A single male who made 46,000, lives in New York, pays 1,150 a month in rent and has about 300 dollars in deductions from interest on a student loan and graduate school tuition?

You can reduce your taxable income by up to $4,000 by deducting your School Tuition fees. It is shown as adjustment to income on Form 1040, line 34 or 1040A, line 19.
Assuming that you will take this adjustment, then on wages of $46,000 the taxes are:
Social security withheld $2852
Medicare withheld $667
Your Federal Income tax $4,736
Then you will have NY Income Tax and other taxes (if any).

He may benefit from the Lifetime Learning Credit rather than the tuitiopn deduction, but I have NOT run the calculations.

Yes, dashman81 will save $600 on tax by claiming tuition deduction. So it may be better not to claim tuition deduction and go for Education credit.

Looking at the original posting, it is NOT clear how much was spent on tuition.

But it's a good bet it's MORE than $4,000.

Maximum tuition fee adjustment allowed is $4,000.

That is true, but I believe the $300 citation is for interest paid.

how much will a single female with 2 children who made about
9000 dollars in seven months lives in waterbury connecticut pays 325 for rent a month

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