I would say not more than 10% of her diet(or less depending on the fat content of her other food) should be these "treats"... I would watch her skin, her stools, and her wieght, if you notice changes cut back. Once a week might be a bit much, maybe closer to once every 10 days. We used to give our dogs "knuckle bones" and the bones you're describing but they were a rare - monthly and only in the fair months of the year, treat.